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KMID : 0377619770320010067
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Korean Jungang Medical Journal
1977 Volume.32 No. 1 p.67 ~ p.76
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A Study on Distribution of LDH Isonezyme Pattern in Normal Fetal Appendage
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Abstract
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For the experiment on the LDH isoenzyme pattern in the normal human fetal appendages (aminon, amniotic-fluid, chorion, umbilical cord), each composition and mean percentage distribution of LDH isoenzyme activities were examined by analysis of quantitative and qualitative studies from early pregnant stage to late stage by agar-gel electrophoresis.
The obtaining results were as following:
1) LDH isoenzyme patterns in normal fetal appendages were classified 5 sub unit by technique of modified electrophoresis on the microscopic slides.
2) LDH isoenzyme patterns of normal amnion, amniotic fluid and umbilical cord showed anaerobic fraction type from early to late pregnant stage and their mean activity rates were increased by increasing of gestational age.
3) The fraction type of LDH isoenzyme in the chorionic tissue of the placenta showed intermediate fraction type with the highest activity rate at LDH III from early pregnant stage to thee ending of pregnant 9th month, but transformations to evident aerobic type were observed in the term placenta. The mean activity of LDH iseonzyme in each sub unit in the chorionic tissue of the term placenta was as follows:
LDH I : 14.72% LDH II :18.20%
LDH III : 27.06% LDH IV : 24.5%
LDH V :15.47%
4) The perfect autoregulation of each tissue or organ metabolism was observed by amicable settlement of LDH isoenzyme sub unit which was mixed harmoniously for physiologic function in normal fetal appendages.
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